Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 13/20 | 0.66 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28644288 | 0.87 | LOX (0.63) | LOXLOXL2KCNH2AOC3LOXL3 | |
| SCHEMBL28638920 | 0.84 | LOX (0.65) | LOXLOXL2ALDH1A1 | |
| SCHEMBL19259860 | 0.80 | LOX (1.00) | LOXLOXL2KCNH2AOC3LOXL3 | |
| SCHEMBL19274568 | 0.80 | LOX (0.77) | LOXLOXL2KCNH2AOC3LOXL3 | |
| SCHEMBL23314105 | 0.80 | LOX (0.66) | LOXLOXL2MEN1KMT2AALDH1A1 | |
| SCHEMBL29287837 | 0.75 | LOX (0.60) | LOXLOXL2MEN1KMT2AALDH1A1 | |
| SCHEMBL28652470 | 0.71 | LOX (0.65) | LOXLOXL2KCNH2AOC3LOXL3 | |
| SCHEMBL28646851 | 0.71 | LOX (0.67) | LOXLOXL2KCNH2AOC3LOXL3 | |
| SCHEMBL28927270 | 0.70 | LOXL2 (0.49) | LOXLOXL2KCNH2AOC3LOXL3 | |
| SCHEMBL28643887 | 0.70 | LOX (0.59) | LOXLOXL2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |