Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30309340 | 0.91 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2L3MBTL1ATM | |
| SCHEMBL24234496 | 0.90 | KDM4E (0.35) | NPC1RAB9ASMN1; SMN2L3MBTL1CASP3 | |
| SCHEMBL736544 | 0.89 | HSD17B10 (0.37) | NPC1RAB9ASMN1; SMN2L3MBTL1ATM | |
| SCHEMBL24234448 | 0.87 | RXRB (0.41) | SSTR5 | |
| SCHEMBL23528871 | 0.87 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2L3MBTL1ATM | |
| SCHEMBL16681006 | 0.85 | HSD17B10 (0.36) | NPC1RAB9ASMN1; SMN2L3MBTL1ATM | |
| SCHEMBL23778669 | 0.81 | PDK2 (0.37) | NPC1RAB9ASMN1; SMN2L3MBTL1CASP3 | |
| SCHEMBL16680931 | 0.81 | PDK2 (0.37) | NPC1RAB9ASMN1; SMN2L3MBTL1CASP3 | |
| SCHEMBL15272062 | 0.80 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL14721679 | 0.80 | MIF (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582987-B | Substituted benzamide isoxazoline derivative or salt acceptable as pesticide, composition and application thereof | 海利尔药业集团股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-113582987-A | Substituted benzamide isoxazoline derivative or salt and composition thereof acceptable as pesticide and application thereof | 海利尔药业集团股份有限公司 | 2021-11-02 | — | — | CN | disclosed |