Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PTPRC | P08575 | 1/20 | 0.53 |
| ▸ | S100A4 | P26447 | 1/20 | 0.53 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586091 | 0.87 | POLB (0.62) | ALOX5CA9CA12CA1CA2 | |
| SCHEMBL13486977 | 0.83 | ALOX5 (0.62) | ALOX5CA9CA12CA1CA2 | |
| SCHEMBL6207633 | 0.83 | ALOX5 (0.62) | ALOX5CA9CA12CA1CA2 | |
| SCHEMBL6956819 | 0.83 | ALOX5 (0.62) | ALOX5CA9CA12CA1CA2 | |
| SCHEMBL2210510 | 0.83 | ALOX5 (0.62) | ALOX5CA9CA12CA1CA2 | |
| SCHEMBL30070354 | 0.83 | ALOX5 (0.62) | ALOX5CA9CA12CA1CA2 | |
| SCHEMBL8083585 | 0.83 | POLB (0.69) | ALOX5CA9CA12CA1CA2 | |
| SCHEMBL4234480 | 0.83 | LPAR3 (0.69) | ALOX5CA9CA12CA1CA2 | |
| SCHEMBL13486978 | 0.82 | POLB (0.67) | ALOX5CA9CA12CA1CA2 | |
| SCHEMBL8686545 | 0.81 | ALOX5 (0.57) | ALOX5CA9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113501777-B | Synthetic method of indoline-5-ylmethylamine dihydrochloride | 上海毕得医药科技股份有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-113501777-A | Synthetic method of indoline-5-ylmethylamine dihydrochloride | 上海毕得医药科技股份有限公司 | 2021-10-15 | — | — | CN | claimed |
| CN-113501777-B | Synthetic method of indoline-5-ylmethylamine dihydrochloride | 上海毕得医药科技股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-113501777-A | Synthetic method of indoline-5-ylmethylamine dihydrochloride | 上海毕得医药科技股份有限公司 | 2021-10-15 | — | — | CN | disclosed |