Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28644203 | 0.80 | HDAC1 (0.41) | LMNAALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL2222966 | 0.68 | LMNA (0.52) | PBRM1LMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL5774816 | 0.67 | LMNA (0.48) | PBRM1LMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL8153650 | 0.66 | SMN1; SMN2 (0.63) | PBRM1LMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL8153652 | 0.66 | SMN1; SMN2 (0.63) | PBRM1LMNAALDH1A1KDM4ERAB9A | |
| SCHEMBL10907125 | 0.66 | MEN1 (0.63) | LMNAALDH1A1RAB9ANPC1HTT | |
| Acetic Acid SCHEMBL17395940 | 0.65 | MEN1 (0.54) | PBRM1LMNAALDH1A1RAB9ANPC1 | |
| Acetic Acid SCHEMBL17395939 | 0.65 | MEN1 (0.54) | PBRM1LMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL5425536 | 0.65 | HPGD (0.62) | LMNAALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL14198041 | 0.65 | LMNA (0.51) | PBRM1LMNAALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074752-B | Therapeutic use of benzylidene guanidine derivatives for the treatment of protein conformation disorders | 英费列特斯生命科学公司 | 2021-10-26 | — | — | CN | disclosed |