SCHEMBL28639485

SCHEMBL28639485

O=C(O)CNC(=O)c1ncc(-c2cn(CCOc3ccc(Cl)cc3)nn2)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28657491 0.91 EGLN1 (0.84) EGLN1
SCHEMBL23562801 0.86 EGLN1 (1.00) EGLN1
Glycine SCHEMBL28651844 0.85 EGLN1 (0.73) EGLN1
SCHEMBL25934719 0.78 EGLN1 (0.85) EGLN1
SCHEMBL28395558 0.76 EGLN1 (0.76) EGLN1
SCHEMBL1920683 0.76 EGLN1 (1.00) EGLN1
SCHEMBL28789754 0.75 EGLN1 (0.59) EGLN1
SCHEMBL25931312 0.74 EGLN1 (1.00) EGLN1
Glycine SCHEMBL28400068 0.74 EGLN1 (0.58) EGLN1
SCHEMBL25280336 0.74 EGLN1 (0.77) EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109593084-B Prolyl hydroxylase small-molecule photosensitive prodrug and preparation method and application thereof 中国药科大学 2021-09-28 CN disclosed