SCHEMBL25934719

SCHEMBL25934719

CC(=O)CNC(=O)c1ncc(-c2cn(CCCc3ccc(Cl)cc3)nn2)cc1O

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23562801 0.92 EGLN1 (1.00) EGLN1
SCHEMBL25280336 0.86 EGLN1 (0.77) EGLN1
SCHEMBL25278826 0.83 EGLN1 (0.69) EGLN1
SCHEMBL31050996 0.83 EGLN1 (0.69) EGLN1
Glycine SCHEMBL28393884 0.80 EGLN1 (0.73) EGLN1
SCHEMBL28639485 0.78 EGLN1 (1.00) EGLN1
SCHEMBL24257551 0.77 EGLN1 (0.70) EGLN1
SCHEMBL28395558 0.75 EGLN1 (0.76) EGLN1
SCHEMBL24257803 0.74 EGLN1 (0.57) EGLN1
SCHEMBL28657491 0.71 EGLN1 (0.84) EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230248717-A1 N-(3-HYDROXYPYRIDINE-2-CARBONYL)GLYCINE-BASED ANTITUMOR DRUG SENSITIZER AND APPLICATION THEREOF ZHEJIANG UNIVERSITY (CN) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230248717-A1 N-(3-HYDROXYPYRIDINE-2-CARBONYL)GLYCINE-BASED ANTITUMOR DRUG SENSITIZER AND APPLICATION THEREOF IDO1, PDCD1, IDO2 EGLN1 37/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.