SCHEMBL28639792

SCHEMBL28639792

C=C(C)C(=O)OCCCc1ccc(O)c(-c2c(Cl)ccc3[nH]nnc23)c1

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MET P08581 2/20 0.31
TNKS2 Q9H2K2 1/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TLR8 Q9NR97 1/20 0.31
IGF1R P08069 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28259139 0.86 TNKS2 (0.33) TNKS2
SCHEMBL28093559 0.84 MET (0.32) METTNKS2POLBAPEX1HTT
SCHEMBL8773777 0.80 IGF1R (0.38) TLR8IGF1RALOX15MAPT
SCHEMBL25184746 0.79 POLB (0.33) METTNKS2POLBAPEX1HTT
SCHEMBL28904239 0.79
SCHEMBL8773796 0.78 FFAR1 (0.45)
SCHEMBL31570222 0.78 APP (0.34) METMAPT
SCHEMBL2934860 0.78 APP (0.34) METMAPT
SCHEMBL8773836 0.78 BACE1 (0.39) IGF1RALOX15MAPT
SCHEMBL28334650 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113573893-A Adhesive composition, adhesive layer and adhesive sheet 日东电工株式会社 2021-10-29 CN disclosed