Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL22664299 | 1.00 | HRH3 (0.71) | HRH3SIGMAR1MAPTCYP1A2MAPK1 | |
| SCHEMBL9680108 | 0.98 | HRH3 (0.75) | HRH3SIGMAR1MAPTCYP1A2MAPK1 | |
| SCHEMBL31518833 | 0.98 | HRH3 (0.75) | HRH3SIGMAR1MAPTCYP1A2MAPK1 | |
| SCHEMBL9678968 | 0.98 | HRH3 (0.75) | HRH3SIGMAR1MAPTCYP1A2MAPK1 | |
| SCHEMBL27973822 | 0.98 | HRH3 (0.75) | HRH3SIGMAR1MAPTCYP1A2MAPK1 | |
| SCHEMBL9677945 | 0.98 | HRH3 (0.75) | HRH3SIGMAR1MAPTCYP1A2MAPK1 | |
| Ammonia Solution, Strong SCHEMBL28716267 | 0.95 | HRH3 (0.71) | HRH3SIGMAR1MAPTCYP1A2MAPK1 | |
| SCHEMBL15743639 | 0.95 | HRH3 (0.70) | HRH3SIGMAR1MAPTCYP1A2MAPK1 | |
| SCHEMBL9680104 | 0.95 | HRH3 (0.70) | HRH3SIGMAR1MAPTCYP1A2MAPK1 | |
| SCHEMBL28716263 | 0.95 | HRH3 (0.70) | HRH3SIGMAR1MAPTCYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113501959-B | Polyether sulphone polymer for vanadium flow battery and preparation method thereof | 常州大学 | 2023-03-03 | — | — | CN | claimed |
| CN-113501959-A | Polyether sulphone polymer for vanadium flow battery and preparation method thereof | 常州大学 | 2021-10-15 | — | — | CN | claimed |
| CN-113501959-B | Polyether sulphone polymer for vanadium flow battery and preparation method thereof | 常州大学 | 2023-03-03 | — | — | CN | disclosed |
| CN-113501959-A | Polyether sulphone polymer for vanadium flow battery and preparation method thereof | 常州大学 | 2021-10-15 | — | — | CN | disclosed |