SCHEMBL28640107

SCHEMBL28640107

CCCCOCO[Si](CCCC)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
TSHR P16473 2/20 0.35
CYP3A4 P08684 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
HPGD P15428 1/20 0.31
ADRB2 P07550 1/20 0.30
ADRB1 P08588 1/20 0.30
ADRB3 P13945 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28201314 0.94 LMNA (0.42) LMNATSHR
SCHEMBL27931303 0.92 LMNA (0.39) LMNA
SCHEMBL29091175 0.92 TSHR (0.35) LMNATSHRCYP3A4SMN1; SMN2HPGD
SCHEMBL28135824 0.89 LMNA (0.44) LMNA
SCHEMBL28281081 0.89 LMNA (0.44) LMNA
SCHEMBL28853041 0.89 LMNA (0.44) LMNA
SCHEMBL28663011 0.89 LMNA (0.37) LMNA
SCHEMBL28875104 0.89 LMNA (0.44) LMNA
SCHEMBL28101376 0.89 LMNA (0.44) LMNA
SCHEMBL27607404 0.86 LMNA (0.38) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113316609-A Solvent-free formulations and nanocomposites 皮瑟莱根特科技有限责任公司 2021-08-27 CN disclosed