SCHEMBL2864047

SCHEMBL2864047

Cc1[nH]c(Cc2ccccc2Cl)nc1-c1ccccc1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.51
LMNA P02545 2/20 0.51
MAPT P10636 1/20 0.51
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
DPP4 P27487 2/20 0.40
GPR84 Q9NQS5 1/20 0.40
POLB P06746 1/20 0.40
CRHR1 P34998 1/20 0.39
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
AR P10275 1/20 0.38
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
PTGS2 P35354 1/20 0.37
PDE3B Q13370 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2867291 0.90 KDM4E (0.48) KDM4ELMNAMAPTKMT2ASMN1; SMN2
SCHEMBL2870088 0.90 KDM4E (0.42) KDM4ELMNAMAPTKMT2ASMN1; SMN2
SCHEMBL3359061 0.89 KDM4E (0.50) KDM4ELMNAMAPTKMT2ASMN1; SMN2
SCHEMBL26112489 0.89 LMNA (0.44) KDM4ELMNAMAPTKMT2AGPR84
SCHEMBL2871376 0.88 KDM4E (0.46) KDM4ELMNAMAPTSMN1; SMN2DPP4
SCHEMBL27967626 0.88 MAPT (0.46) KDM4ELMNAMAPTKMT2ASMN1; SMN2
SCHEMBL31305427 0.88 KDM4E (0.46) KDM4ELMNAMAPTSMN1; SMN2DPP4
SCHEMBL26111667 0.88 HTT (0.43) KDM4ELMNAMAPTKMT2ASMN1; SMN2
SCHEMBL27967688 0.88 EGFR (0.41) KDM4ELMNAMAPTKMT2ASMN1; SMN2
SCHEMBL28812702 0.87 MAPT (0.48) KDM4ELMNAMAPTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102119240-B Surface treating agent for copper or copper alloy and use thereof SHIKOKU CHEM 2014-07-30 CN disclosed
WO-2010016620-A1 SURFACE TREATING AGENT FOR COPPER OR COPPER ALLOY AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2010-02-11 WO disclosed