Known targets — ChEMBL curated mechanism
CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8
The experimentally established mechanism targets of Phloroglucinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43101 | 0.87 | — | — | |
| Phenol SCHEMBL28136585 | 0.86 | CA12 (0.44) | GAAKMT2AMEN1LMNAMAPT | |
| Phenol SCHEMBL28381926 | 0.86 | CA12 (0.44) | GAAKMT2AMEN1LMNAMAPT | |
| Methane SCHEMBL28113921 | 0.84 | — | — | |
| SCHEMBL27581592 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL27707333 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL2389399 | 0.84 | — | — | |
| Ammonia Solution, Strong SCHEMBL28482817 | 0.84 | — | — | |
| Fluoride SCHEMBL7045998 | 0.82 | KMT2A (0.46) | GAAKMT2AMEN1MAPTALDH1A1 | |
| Ethylenediamine SCHEMBL28193 | 0.82 | KMT2A (0.46) | GAAKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110128611-B | Low-temperature curing bio-based benzoxazine resin and preparation method thereof | 浙江大学宁波理工学院 | 2021-10-22 | — | — | CN | claimed |
| CN-110128611-B | Low-temperature curing bio-based benzoxazine resin and preparation method thereof | 浙江大学宁波理工学院 | 2021-10-22 | — | — | CN | disclosed |