SCHEMBL28640552

SCHEMBL28640552

C=Cc1ccc(N(C)C)cc1OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.47
ALDH1A1 P00352 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
NQO2 P16083 1/20 0.45
CYP1A2 P05177 7/20 0.44
CYP1A1 P04798 6/20 0.44
CYP1B1 Q16678 6/20 0.44
TUBB4A P04350 1/20 0.44
TUBB P07437 1/20 0.44
TUBA3C P0DPH7 1/20 0.44
TUBA1B P68363 1/20 0.44
TUBA4A P68366 1/20 0.44
TUBB4B P68371 1/20 0.44
TUBB3 Q13509 1/20 0.44
TUBB2A Q13885 1/20 0.44
TUBB8 Q3ZCM7 1/20 0.44
TUBA3E Q6PEY2 1/20 0.44
TUBA1A Q71U36 1/20 0.44
TUBA1C Q9BQE3 1/20 0.44
TUBB6 Q9BUF5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18459891 0.82 CYP1A1 (0.56) BACE1ALDH1A1NQO2CYP1A2CYP1A1
SCHEMBL154497 0.81 ALDH1A1 (0.68) BACE1ALDH1A1L3MBTL1NQO2CYP1A2
SCHEMBL11289010 0.81 ALDH1A1 (0.71) ALDH1A1L3MBTL1CYP1A2CYP1A1CYP1B1
SCHEMBL25746980 0.79 CYBB (0.49) BACE1ALDH1A1L3MBTL1CYBBNOX4
SCHEMBL28639990 0.79 CYP1A2 (0.44) BACE1ALDH1A1L3MBTL1NQO2CYP1A2
SCHEMBL3627239 0.79 CYP1A2 (0.70) ALDH1A1CYP1A2CYP1A1CYP1B1NFE2L2
SCHEMBL30411244 0.79 CYP1A2 (0.70) ALDH1A1CYP1A2CYP1A1CYP1B1NFE2L2
SCHEMBL13236413 0.78 ALDH1A1 (0.55) ALDH1A1L3MBTL1CYP1A2CYP1A1CYP1B1
SCHEMBL10771723 0.78 NQO2 (0.47) ALDH1A1NQO2TUBB4ATUBBTUBA3C
SCHEMBL22203787 0.77 MAPT (0.48) BACE1ALDH1A1L3MBTL1NQO2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113402514-B Organic dye compound and preparation method and application thereof 南方医科大学 2022-05-03 CN disclosed
CN-113402514-A Organic dye compound and preparation method and application thereof 南方医科大学 2021-09-17 CN disclosed