SCHEMBL28640563

SCHEMBL28640563

c1ccc(COCCOCCOCCOCCOCCNC(c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.49
TSHR P16473 1/20 0.45
MIF P14174 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NAAA Q02083 1/20 0.44
LMNA P02545 1/20 0.44
HTT P42858 1/20 0.43
KCNN4 O15554 1/20 0.43
CHRM3 P20309 3/20 0.39
CHRM2 P08172 2/20 0.39
CHRM1 P11229 2/20 0.39
FOXM1 Q08050 1/20 0.39
SLC6A2 P23975 1/20 0.39
PDE4A P27815 1/20 0.39
SLC6A4 P31645 1/20 0.39
OPRM1 P35372 1/20 0.39
SLC6A3 Q01959 1/20 0.39
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30871692 0.89 CHRM3 (0.47) KIF11TSHRMIFSMN1; SMN2HTT
SCHEMBL7263691 0.84 KIF11 (0.53) KIF11TSHRMIFSMN1; SMN2LMNA
SCHEMBL7263720 0.81 KIF11 (0.65) KIF11TSHRMIFSMN1; SMN2LMNA
SCHEMBL20823126 0.81 KIF11 (0.50) KIF11MIFSMN1; SMN2LMNAHTT
SCHEMBL25601858 0.81 KIF11 (0.50) KIF11MIFSMN1; SMN2LMNAKCNN4
SCHEMBL7268298 0.81 KIF11 (0.65) KIF11TSHRMIFSMN1; SMN2LMNA
SCHEMBL17980741 0.79 KIF11 (0.52) KIF11MIFSMN1; SMN2LMNAKCNN4
SCHEMBL7268289 0.79 KIF11 (0.67) KIF11TSHRMIFSMN1; SMN2KCNN4
SCHEMBL17980744 0.79 KIF11 (0.52) KIF11TSHRMIFSMN1; SMN2LMNA
SCHEMBL10065919 0.79 KIF11 (0.55) KIF11MIFSMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113480453-B Synthesis method of NH2-PEG5-NHBoc 苏州昊帆生物股份有限公司 2023-04-04 CN claimed
CN-113480453-A Synthesis method of NH2-PEG5-NHBoc 苏州昊帆生物股份有限公司 2021-10-08 CN claimed
CN-113480453-B Synthesis method of NH2-PEG5-NHBoc 苏州昊帆生物股份有限公司 2023-04-04 CN disclosed
CN-113480453-A Synthesis method of NH2-PEG5-NHBoc 苏州昊帆生物股份有限公司 2021-10-08 CN disclosed