SCHEMBL28640652

SCHEMBL28640652

O=Cc1cc(-c2c(O)c(C=O)cc3ccccc23)c2ccccc2c1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 13/20 0.51
NQO1 P15559 1/20 0.41
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
MPI P34949 1/20 0.35
KMT2A Q03164 1/20 0.35
PADI4 Q9UM07 1/20 0.34
PIM1 P11309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30979185 1.00 ERN1 (0.51) ERN1NQO1KDM4EMEN1ALDH1A1
Acrylic Acid SCHEMBL30071658 0.91 ERN1 (0.44) ERN1NQO1KDM4EMEN1ALDH1A1
SCHEMBL354162 0.85 ERN1 (0.54) ERN1NQO1
SCHEMBL29618439 0.85 ERN1 (0.54) ERN1NQO1
SCHEMBL30071644 0.84 ERN1 (0.63) ERN1NQO1MEN1MAPTKMT2A
SCHEMBL31152504 0.84 ERN1 (0.63) ERN1NQO1MEN1MAPTKMT2A
SCHEMBL2943970 0.84 ERN1 (0.63) ERN1NQO1MEN1MAPTKMT2A
SCHEMBL30539187 0.76 MEN1 (0.55) ERN1KDM4EMEN1MAPTKMT2A
SCHEMBL3416460 0.76 MEN1 (0.55) ERN1KDM4EMEN1MAPTKMT2A
SCHEMBL10331756 0.76 ERN1 (0.65) ERN1NQO1PADI4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271241-A Axis chiral nitrogen-containing heteroaromatic ring polydentate ligand, preparation method and application thereof 华东理工大学 2024-07-02 CN disclosed
CN-109593049-B Binaphthol solid fluorescent material 青岛科技大学 2021-09-24 CN disclosed