SCHEMBL354162

SCHEMBL354162

O=Cc1cc2ccccc2c(-c2cccc3ccccc23)c1O

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 12/20 0.54
GPR84 Q9NQS5 1/20 0.43
CES1 P23141 1/20 0.41
NQO1 P15559 1/20 0.40
MCL1 Q07820 1/20 0.39
ACMSD Q8TDX5 1/20 0.39
SOS1 Q07889 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29618439 1.00 ERN1 (0.54) ERN1GPR84CES1NQO1MCL1
SCHEMBL30071644 0.87 ERN1 (0.63) ERN1NQO1
SCHEMBL2943970 0.87 ERN1 (0.63) ERN1NQO1
SCHEMBL31152504 0.87 ERN1 (0.63) ERN1NQO1
SCHEMBL30979185 0.85 ERN1 (0.51) ERN1NQO1
SCHEMBL28640652 0.85 ERN1 (0.51) ERN1NQO1
SCHEMBL31490177 0.83 CES1 (0.41) ERN1GPR84CES1SOS1
SCHEMBL3416460 0.81 MEN1 (0.55) ERN1
SCHEMBL30539187 0.81 MEN1 (0.55) ERN1
SCHEMBL12961715 0.80 ERN1 (0.52) ERN1NQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160254-B Chiral fluorescent probe with benzothiazole group and preparation and application thereof 武汉工程大学 2023-10-31 CN claimed
CN-115043762-B Chiral fluorescent probe containing perfluoroalkyl, preparation method and application thereof 武汉工程大学 2023-07-11 CN claimed
CN-115160254-A Chiral fluorescent probe with benzothiazole group and preparation and application thereof 武汉工程大学 2022-10-11 CN claimed
CN-115043762-A Chiral fluorescent probe containing perfluoroalkyl and preparation method and application thereof 武汉工程大学 2022-09-13 CN claimed
CN-114591209-A BINOL-based fluorescent probe, synthetic method thereof and application thereof in cadmium ion detection 兰州大学 2022-06-07 CN claimed
CN-115160254-B Chiral fluorescent probe with benzothiazole group and preparation and application thereof 武汉工程大学 2023-10-31 CN disclosed
CN-115160254-B Chiral fluorescent probe with benzothiazole group and preparation and application thereof 武汉工程大学 2023-10-31 CN disclosed
CN-115043762-B Chiral fluorescent probe containing perfluoroalkyl, preparation method and application thereof 武汉工程大学 2023-07-11 CN disclosed
CN-115043762-B Chiral fluorescent probe containing perfluoroalkyl, preparation method and application thereof 武汉工程大学 2023-07-11 CN disclosed
CN-115160254-A Chiral fluorescent probe with benzothiazole group and preparation and application thereof 武汉工程大学 2022-10-11 CN disclosed
CN-115043762-A Chiral fluorescent probe containing perfluoroalkyl and preparation method and application thereof 武汉工程大学 2022-09-13 CN disclosed
CN-114591209-A BINOL-based fluorescent probe, synthetic method thereof and application thereof in cadmium ion detection 兰州大学 2022-06-07 CN disclosed
WO-2022035228-A1 AMINO ACID EXTRACTION PROCESS USING T-BUTYL KETONE BINAPHTHOL DERIVATIVE OR T-BUTYL KETONE DERIVATIVE, AND CONTINUOUS REACTOR FOR PERFORMING SAME 이화여자대학교 산학협력단 2022-02-17 WO disclosed
US-8865933-B2 Method for obtaining optically pure amino acids AMINOLOGICS CO., LTD. (KR) 2014-10-21 US disclosed
EP-2412704-A2 METHOD FOR OBTAINING OPTICALLY PURE AMINO ACIDS Aminolux, Inc. (KR) 2012-02-01 EP disclosed
US-20120016157-A1 METHOD FOR OBTAINING OPTICALLY PURE AMINO ACIDS AMINOLOGICS CO., LTD. (KR) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120016157-A1 METHOD FOR OBTAINING OPTICALLY PURE AMINO ACIDS OGFR, AADAT, DAO ERN1 2616/4885GPR84 90/4885CES1 3255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.