Dimedazol

Dimedazol

SCHEMBL28640693

Cc1cc2nc[nH]c2cc1C.Fc1c(F)c(F)c(N(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
KDM4E B2RXH2 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 1/20 0.41
APEX1 P27695 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
QPCT Q16769 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
MMP12 P39900 1/20 0.36
PRKCI P41743 1/20 0.35
PKM P14618 1/20 0.35
RAD52 P43351 1/20 0.34
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimedazol SCHEMBL312977 0.82 MAPT (0.56) MAPTKDM4ETDP1ALDH1A1APEX1
Dimedazol SCHEMBL28639998 0.82 MAPT (0.45) MAPTKDM4ETDP1ALDH1A1APEX1
Dimedazol SCHEMBL61387 0.82 MAPT (0.45) MAPTKDM4ETDP1ALDH1A1APEX1
Dimedazol SCHEMBL28621495 0.81 MAPT (0.44) MAPTKDM4ETDP1ALDH1A1APEX1
Dimedazol SCHEMBL61658 0.81 MAPT (0.44) MAPTKDM4ETDP1ALDH1A1APEX1
Dimedazol SCHEMBL726090 0.77 MAPT (0.41) MAPTKDM4ETDP1ALDH1A1APEX1
Dimedazol SCHEMBL727732 0.76 MAPT (0.40) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL12113061 0.75 MAPT (0.61) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL12121772 0.75 MAPT (0.56) MAPTKDM4ETDP1ALDH1A1APEX1
Dimedazol SCHEMBL29097803 0.74 MAPT (0.47) MAPTKDM4ETDP1ALDH1A1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113412264-B Organometallic chain transfer agent 陶氏环球技术有限责任公司 2024-06-25 CN disclosed
CN-113498413-A Curable compositions comprising unsaturated polyolefins 陶氏环球技术有限责任公司 2021-10-12 CN disclosed
CN-113498414-A Curable compositions comprising telechelic polyolefins 陶氏环球技术有限责任公司 2021-10-12 CN disclosed
CN-113490714-A Curable compositions comprising unsaturated polyolefins 陶氏环球技术有限责任公司 2021-10-08 CN disclosed
CN-113474405-A Curable compositions comprising unsaturated polyolefins 陶氏环球技术有限责任公司 2021-10-01 CN disclosed
CN-113454130-A Telechelic polyolefins and process for preparing telechelic polyolefins 陶氏环球技术有限责任公司 2021-09-28 CN disclosed
CN-113454091-A Curable compositions comprising unsaturated polyolefins 陶氏环球技术有限责任公司 2021-09-28 CN disclosed
CN-113454152-A Curable compositions comprising unsaturated polyolefins 陶氏环球技术有限责任公司 2021-09-28 CN disclosed
CN-113412264-A Organometallic chain transfer agents 陶氏环球技术有限责任公司 2021-09-17 CN disclosed