Dimedazol

Dimedazol

SCHEMBL312977

Cc1cc2nc[nH]c2cc1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.56
KDM4E B2RXH2 4/20 0.56
TDP1 Q9NUW8 2/20 0.56
ALDH1A1 P00352 1/20 0.56
APEX1 P27695 1/20 0.56
RECQL P46063 1/20 0.56
BLM P54132 1/20 0.56
MMP12 P39900 1/20 0.47
PRKCI P41743 1/20 0.47
RAD52 P43351 1/20 0.45
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CHRNB2 P17787 1/20 0.43
CHRNA4 P43681 1/20 0.43
FABP6 P51161 1/20 0.42
CYP3A4 P08684 1/20 0.41
NAMPT P43490 1/20 0.41
XDH P47989 1/20 0.41
BRD4 O60885 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimedazol SCHEMBL29097803 0.90 MAPT (0.47) MAPTKDM4ETDP1ALDH1A1APEX1
Dimedazol SCHEMBL28394195 0.88 KDM4E (0.46) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL31268592 0.85 MAPT (0.50) MAPTKDM4ETDP1ALDH1A1APEX1
Dimedazol SCHEMBL61387 0.84 MAPT (0.45) MAPTKDM4ETDP1ALDH1A1APEX1
Dimedazol SCHEMBL28639998 0.84 MAPT (0.45) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL3891260 0.83 MAPT (0.56) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL1839055 0.83 MAPT (0.70) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL13373332 0.83 MAPT (0.48) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL12113061 0.83 MAPT (0.61) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL3925343 0.83 MAPT (0.48) MAPTKDM4ETDP1ALDH1A1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1877 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122060375-A Corrosion-resistant fireproof explosion-proof material, preparation method thereof and application thereof in electric power tunnel 南昌泰事达电气科技有限公司 2026-05-19 CN claimed
CN-122063164-A Application of composite hollow nanotube array with core-sheath structure and coated with MOF hydrophobic layer in gas-sensitive moisture resistance 中国科学院福建物质结构研究所 2026-05-19 CN claimed
US-12550694-B2 Selective deposition for integrated circuit interconnect structures TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2026-02-10 US claimed
US-12496548-B2 Hydrophobic MOF-based porous liquid carbon capture absorbent and preparation method therefor HUANENG CLEAN ENERGY RESEARCH INSTITUTE (CN) 2025-12-16 US claimed
CN-119994394-A Diaphragm, preparation method thereof and lithium ion battery 蜂巢能源科技股份有限公司 2025-05-13 CN claimed
CN-116093348-B Preparation method of cobalt-nitrogen-carbon material with high electrocatalytic performance 中钢集团南京新材料研究院有限公司 2025-04-29 CN claimed
CN-119505275-B MOF-CGC material and preparation method and application thereof 宁波大学 2025-04-29 CN claimed
US-12278143-B2 Method of providing a workpiece including low resistance interconnect low-resistance interconnect TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2025-04-15 US claimed
CN-119793232-A MOF crystal-glass composite membrane for gas separation and preparation method and application thereof 衢州膜材料创新研究院 2025-04-11 CN claimed
US-5405839-A Vitamin B12 antagonist; inhibits cell growth; anticancer agents TEIJIN LIMITED (JP) 1995-04-11 US claimed
EP-0251760-B1 Rubber composition BRIDGESTONE CORP (JP) 1994-01-26 EP claimed
US-5140055-A Improved high speed grip performance BRIDGESTONE CORPORATION (JP) 1992-08-18 US claimed
US-4752584-A Process for the production of inoculum for anaerobic fermentation of coenzyme B12 RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1988-06-21 US claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed
US-4659661-A Process for the preparation of fermentation broth for coenzyme B12 and other corrinoid production RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1987-04-21 US claimed
EP-0030684-B1 TEST COMPOSITION FOR PEROXIDATIVELY ACTIVE SUBSTANCES, TEST DEVICE CONTAINING THE COMPOSITION, PROCESS FOR PREPARING SAME AND METHOD FOR THE DETERMINATION OF PEROXIDATIVELY ACTIVE SUBSTANCES MILES LABORATORIES, INC. (US) 1983-03-16 EP claimed
US-4329459-A ENDOPEROXIDE CYCLOXGENASE INHIBITORS THE UPJOHN COMPANY (US) 1982-05-11 US claimed
US-4278439-A BENZIMIDAZOLES MILES LABORATORIES, INC. (US) 1981-07-14 US claimed
EP-0030684-A1 Test composition for peroxidatively active substances, test device containing the composition, process for preparing same and method for the determination of peroxidatively active substances MILES LABORATORIES, INC. (US) 1981-06-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12550694-B2 Selective deposition for integrated circuit interconnect structures CAPRIN1, PIEZO1, GJB2 MAPT 2143/4885KDM4E 279/4885TDP1 1727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.