SCHEMBL28640852

SCHEMBL28640852

FC(=Cc1cccc2ccccc12)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
GAA P10253 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
CRHBP P24387 1/20 0.41
HTT P42858 1/20 0.41
CRHR2 Q13324 1/20 0.41
GRIN2D O15399 2/20 0.41
GRIN3B O60391 2/20 0.41
GRIN1 Q05586 2/20 0.41
GRIN2A Q12879 2/20 0.41
GRIN2B Q13224 2/20 0.41
GRIN2C Q14957 2/20 0.41
GRIN3A Q8TCU5 2/20 0.41
EGFR P00533 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28651825 1.00 KDM4E (0.45) KDM4EMEN1KMT2AGAAALDH1A1
SCHEMBL28640850 1.00 KDM4E (0.45) KDM4EMEN1KMT2AGAAALDH1A1
SCHEMBL7695549 0.81 KDM4E (0.47) KDM4EMEN1KMT2AGAAALDH1A1
SCHEMBL5067795 0.80 KDM4E (0.46) KDM4EMEN1KMT2AGAAALDH1A1
SCHEMBL8546758 0.78 GRIN2D (0.49) KDM4EMEN1KMT2AGAAALDH1A1
SCHEMBL22325527 0.78 KDM4E (0.45) KDM4EMEN1KMT2AGAAALDH1A1
SCHEMBL10649030 0.78 KDM4E (0.53) KDM4EMEN1KMT2AGAAALDH1A1
SCHEMBL22325528 0.78 KDM4E (0.45) KDM4EMEN1KMT2AGAAALDH1A1
SCHEMBL8546766 0.78 GRIN2D (0.49) KDM4EMEN1KMT2AGAAALDH1A1
SCHEMBL10649027 0.78 KDM4E (0.53) KDM4EMEN1KMT2AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447521-B Reagent for preparing high-selectivity monofluoroolefin 中国科学院上海有机化学研究所 2021-09-03 CN disclosed