Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29278550 | 0.84 | BACE1 (0.43) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31172233 | 0.83 | KDM4E (0.51) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28651825 | 0.80 | KDM4E (0.45) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28640852 | 0.80 | KDM4E (0.45) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28640850 | 0.80 | KDM4E (0.45) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28492926 | 0.79 | KDM4E (0.55) | KDM4EHDAC8HDAC6MTNR1AMTNR1B | |
| SCHEMBL6234937 | 0.78 | GRIN2D (0.55) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28201552 | 0.78 | GRIN2D (0.59) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6027912 | 0.78 | KDM4E (0.54) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13032947 | 0.78 | NFE2L2 (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466891-A | Preparation method of 2-fluoropyrazolo [1,5-a ] pyridine compound | 西北师范大学 | 2024-01-30 | — | — | CN | disclosed |
| US-20230416266-A1 | 6,7-DIHYDRO-PYRANO[2,3-d]PYRIMIDINE INHIBITORS OF KRAS G12C MUTANT | MERCK SHARP & DOHME LLC | 2023-12-28 | — | — | US | disclosed |
| EP-4247807-A1 | 6,7-DIHYDRO-PYRANO[2,3-D]PYRIMIDINE INHIBITORS OF KRAS G12C MUTANT | Merck Sharp & Dohme LLC (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-114436919-B | Alpha-difluoro sulfur methyl ketone (alcohol) derivative and synthetic method thereof | 华南理工大学 | 2023-01-06 | — | — | CN | disclosed |
| WO-2022109485-A1 | 6,7-DIHYDRO-PYRANO[2,3-D]PYRIMIDINE INHIBITORS OF KRAS G12C MUTANT | MERCK SHARP & DOHME CORP. (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022109485-A1 | 6,7-DIHYDRO-PYRANO[2,3-D]PYRIMIDINE INHIBITORS OF KRAS G12C MUTANT | MERCK SHARP & DOHME CORP. (US) | 2022-05-27 | — | — | WO | disclosed |
| CN-114436919-A | Alpha-difluoro sulfur methyl ketone (alcohol) derivative and synthetic method thereof | 华南理工大学 | 2022-05-06 | — | — | CN | disclosed |
| US-8148006-B2 | Electrolytic solution and battery | SONY CORPORATION (JP) | 2012-04-03 | — | — | US | disclosed |
| US-8148006-B2 | Electrolytic solution and battery | SONY CORPORATION (JP) | 2012-04-03 | — | — | US | disclosed |
| US-7829603-B2 | Stable trifluorostyrene containing compounds grafted to base polymers, and their use as polymer electrolyte membranes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-09 | — | — | US | disclosed |
| US-7737190-B2 | Process to prepare stable trifluorostyrene containing compounds grafted to base polymers using a solvent/water mixture | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-15 | — | — | US | disclosed |
| US-7563532-B2 | Trifluorostyrene containing compounds, and their use in polymer electrolyte membranes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-21 | — | — | US | disclosed |
| US-20080292970-A1 | ELECTROLYTIC SOLUTION AND BATTERY | SONY CORPORATION (JP) | 2008-11-27 | — | — | US | disclosed |
| US-20080292970-A1 | ELECTROLYTIC SOLUTION AND BATTERY | SONY CORPORATION (JP) | 2008-11-27 | — | — | US | disclosed |
| US-20080206624-A1 | Trifluorostyrene Containing Compounds, and their Use in Polymer Electrolyte Membranes | U.S. DEPARTMENT OF ENERGY | 2008-08-28 | — | — | US | disclosed |
| JP-2008174562-A | PHOTOACID GENERATOR AND PHOTORESIST CONTAINING THE SAME | ROHM & HAAS ELECTRONIC MATERIALS LLC | 2008-07-31 | — | — | JP | disclosed |
| US-20080032184-A1 | Stable Trifluorostyrene Containing Compounds, And Their Use In Polymer Electroyte Membranes | U.S. DEPARTMENT OF ENERGY | 2008-02-07 | — | — | US | disclosed |
| US-20070208092-A1 | Stable Trifluorostyrene Containing Compounds Grafted To Base Polymers, And Their Use As Polymer Electrolyte Membranes | U.S. DEPARTMENT OF ENERGY | 2007-09-06 | — | — | US | disclosed |
| US-6849374-B2 | Photoacid generators and photoresists comprising same | SHIPLEY COMPANY, L.L.C. (US) | 2005-02-01 | — | — | US | disclosed |
| US-20030027061-A1 | Photoacid generators and photoresists comprising same | SHIPLEY COMPANY, L.L.C. | 2003-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080032184-A1 | Stable Trifluorostyrene Containing Compounds, And Their Use In Polymer Electroyte Membranes | NHERF1, AFF1, SLCO2A1 | KDM4E 2754/4885GRIN2D 824/4885GRIN3B 1452/4885 |
| US-20230416266-A1 | 6,7-DIHYDRO-PYRANO[2,3-d]PYRIMIDINE INHIBITORS OF KRAS G12C MUTANT | KRAS, NRAS, HRAS | KDM4E 2685/4885GRIN2D 2748/4885GRIN3B 3652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.