Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 3/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599882 | 0.75 | MAPT (1.00) | MAPTKMT2AMEN1KDM4ETDP1 | |
| SCHEMBL16080104 | 0.75 | MAPT (1.00) | MAPTKMT2AMEN1KDM4ETDP1 | |
| SCHEMBL7599877 | 0.75 | MAPT (1.00) | MAPTKMT2AMEN1KDM4ETDP1 | |
| SCHEMBL28640894 | 0.75 | ALOX5 (0.36) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28621549 | 0.75 | KMT2A (0.44) | MAPTKMT2AMEN1KDM4ETDP1 | |
| SCHEMBL28629281 | 0.70 | KDM4E (0.36) | MAPTKDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL10577130 | 0.64 | MAPT (0.77) | MAPTKMT2AMEN1KDM4ETDP1 | |
| SCHEMBL10577132 | 0.64 | MAPT (0.77) | MAPTKMT2AMEN1KDM4ETDP1 | |
| SCHEMBL10577536 | 0.62 | MAPT (0.74) | MAPTKMT2AMEN1KDM4ETDP1 | |
| SCHEMBL10577532 | 0.62 | MAPT (0.74) | MAPTKMT2AMEN1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250174-B | Naphthopyran compounds and preparation method thereof | 中国科学院兰州化学物理研究所苏州研究院 | 2021-09-10 | — | — | CN | disclosed |