SCHEMBL2864101

SCHEMBL2864101

Cc1cccc(-c2cc(O)ccc2O)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.49
GAA P10253 2/20 0.49
SI P14410 2/20 0.49
MGAM2 Q2M2H8 2/20 0.49
TRPA1 O75762 2/20 0.48
ATM Q13315 1/20 0.48
TLR8 Q9NR97 1/20 0.45
ANPEP P15144 1/20 0.44
DPP4 P27487 1/20 0.44
CHEK1 O14757 1/20 0.43
WEE1 P30291 1/20 0.43
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
AMY1A P0DUB6 1/20 0.41
ESR2 Q92731 3/20 0.40
ALDH1A1 P00352 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2860157 0.86 TRPA1 (0.50) MGAMGAASIMGAM2TRPA1
SCHEMBL28597257 0.86 ATM (0.45) MGAMGAASIMGAM2TRPA1
Pyrophosphoric Acid SCHEMBL29150573 0.86 MGAM (0.40) MGAMGAASIMGAM2TRPA1
SCHEMBL17753386 0.85 GAA (0.49) MGAMGAASIMGAM2TRPA1
SCHEMBL1163819 0.84 HPGD (0.49) MGAMGAASIMGAM2ATM
SCHEMBL27726545 0.83 CYP1A2 (0.48) MGAMGAASIMGAM2TRPA1
SCHEMBL8373514 0.82 ESR2 (0.55) TRPA1ATMANPEPDPP4CHEK1
SCHEMBL6572360 0.81 PDE10A (0.57) GAATRPA1ATMANPEPDPP4
Hydrochloric Acid SCHEMBL6788845 0.80 PDE10A (0.55) GAATRPA1ATMTLR8ANPEP
SCHEMBL28305291 0.80 GAA (0.51) MGAMGAASIMGAM2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108431297-A The manufacturing method of laser direct forming layer formation composition, component and the synthetic resin with coating 三菱工程塑料株式会社 2018-08-21 CN disclosed
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
US-20080032086-A1 Radial Tilt Reduced Media GENERAL ELECTRIC COMPANY (US) 2008-02-07 US disclosed
CN-100364160-C Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES (JP) 2008-01-23 CN disclosed
US-7309518-B2 Radial tilt reduced media GENERAL ELECTRIC COMPANY (US) 2007-12-18 US disclosed
US-7300690-B2 Radial tilt reduced media GENERAL ELECTRIC COMPANY (US) 2007-11-27 US disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed
US-20050202201-A1 Radial tilt reduced media CITIBANK, N.A., AS COLLATERAL AGENT 2005-09-15 US disclosed
US-20050180284-A1 Radial tilt reduced media HAY GRANT (US) 2005-08-18 US disclosed
EP-1459310-A1 RADIAL TILT REDUCED MEDIA GENERAL ELECTRIC COMPANY (US) 2004-09-22 EP disclosed
WO-2003052757-A1 RADIAL TILT REDUCED MEDIA GENERAL ELECTRIC COMPANY (US) 2003-06-26 WO disclosed
US-20020197438-A1 Radial tilt reduced media CITIBANK, N.A., AS COLLATERAL AGENT 2002-12-26 US disclosed