Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.71 |
| ▸ | STAT3 | P40763 | 4/20 | 0.71 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22092695 | 0.91 | TYK2 (0.69) | TYK2STAT3 | |
| SCHEMBL28557220 | 0.86 | TYK2 (0.71) | TYK2STAT3HPGDS | |
| SCHEMBL28641308 | 0.85 | TYK2 (0.76) | TYK2STAT3 | |
| SCHEMBL22092690 | 0.83 | TYK2 (1.00) | TYK2STAT3 | |
| SCHEMBL22103760 | 0.83 | TYK2 (1.00) | TYK2STAT3 | |
| SCHEMBL24224244 | 0.83 | TYK2 (1.00) | TYK2STAT3 | |
| SCHEMBL30377885 | 0.83 | TYK2 (1.00) | TYK2STAT3 | |
| SCHEMBL21887786 | 0.76 | TYK2 (0.69) | TYK2STAT3HPGDS | |
| SCHEMBL21887373 | 0.76 | TYK2 (0.59) | TYK2STAT3HPGDS | |
| SCHEMBL22092672 | 0.76 | TYK2 (0.47) | TYK2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166163-B | 7- (methylamino) pyrazolo [1,5-A ] pyrimidine-3-carboxamide derivatives | 伊莱利利公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-113166163-A | 7- (methylamino) pyrazolo [1,5-A ] pyrimidine-3-carboxamide derivatives | 伊莱利利公司 | 2021-07-23 | — | — | CN | disclosed |