Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4855546 | 0.89 | HRH3 (0.74) | HRH3SMN1; SMN2GAAOPRK1CARM1 | |
| SCHEMBL12642623 | 0.88 | HRH3 (0.61) | HRH3SMN1; SMN2GAAOPRK1CARM1 | |
| SCHEMBL5203366 | 0.82 | HRH3 (0.69) | HRH3SMN1; SMN2GAAOPRK1ROCK2 | |
| SCHEMBL28633821 | 0.82 | HRH3 (0.57) | HRH3SMN1; SMN2GAAOPRK1CARM1 | |
| SCHEMBL13463052 | 0.81 | HRH3 (0.70) | HRH3SMN1; SMN2GAAOPRK1ROCK2 | |
| SCHEMBL3022526 | 0.81 | HRH3 (0.71) | HRH3SMN1; SMN2GAAOPRK1ROCK2 | |
| SCHEMBL8393625 | 0.81 | HRH3 (0.71) | HRH3SMN1; SMN2GAAOPRK1ROCK2 | |
| SCHEMBL10607825 | 0.80 | HRH3 (0.62) | HRH3SMN1; SMN2GAAOPRK1CARM1 | |
| SCHEMBL5207650 | 0.80 | HRH3 (0.70) | HRH3SMN1; SMN2GAAOPRK1ROCK2 | |
| SCHEMBL1895869 | 0.79 | HRH3 (0.69) | HRH3SMN1; SMN2GAAOPRK1CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454086-B | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-113454086-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2021-09-28 | — | — | CN | disclosed |