Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632536 | 0.87 | TDP1 (0.65) | TDP1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL28640023 | 0.84 | KDM4E (0.69) | TDP1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL28870519 | 0.84 | KDM4E (0.69) | TDP1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL28635282 | 0.84 | TDP1 (0.61) | TDP1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL28637135 | 0.84 | KDM4E (0.66) | TDP1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL28925276 | 0.83 | GPR183 (0.63) | TDP1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL28632925 | 0.82 | ALDH1A1 (0.66) | TDP1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL28640191 | 0.82 | KDM4E (0.66) | TDP1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL28925278 | 0.81 | TDP1 (0.62) | TDP1KDM4EALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL28643937 | 0.79 | TDP1 (0.60) | TDP1KDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461639-B | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2022-11-01 | — | — | CN | claimed |
| CN-113461639-A | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2021-10-01 | — | — | CN | claimed |
| CN-113461639-B | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-113461639-A | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2021-10-01 | — | — | CN | disclosed |