Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB4 | Q16877 | 13/20 | 0.94 |
| ▸ | PFKFB3 | Q16875 | 12/20 | 0.94 |
| ▸ | CMA1 | P23946 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788108 | 0.97 | PFKFB4 (1.00) | PFKFB4PFKFB3CMA1NPSR1L3MBTL1 | |
| SCHEMBL3555875 | 0.90 | PFKFB3 (0.83) | PFKFB4PFKFB3CMA1NPSR1L3MBTL1 | |
| SCHEMBL788429 | 0.88 | PFKFB3 (0.87) | PFKFB4PFKFB3CMA1NPSR1L3MBTL1 | |
| SCHEMBL3553777 | 0.86 | PFKFB3 (0.77) | PFKFB4PFKFB3CMA1NPSR1L3MBTL1 | |
| SCHEMBL787869 | 0.86 | PFKFB3 (1.00) | PFKFB4PFKFB3CMA1NPSR1L3MBTL1 | |
| SCHEMBL5621758 | 0.86 | PFKFB3 (0.80) | PFKFB4PFKFB3CMA1NPSR1L3MBTL1 | |
| SCHEMBL788058 | 0.85 | PFKFB3 (1.00) | PFKFB4PFKFB3CMA1NPSR1L3MBTL1 | |
| SCHEMBL788073 | 0.85 | PFKFB3 (0.88) | PFKFB4PFKFB3CMA1NPSR1L3MBTL1 | |
| SCHEMBL788794 | 0.84 | PFKFB3 (0.86) | PFKFB4PFKFB3CMA1NPSR1L3MBTL1 | |
| SCHEMBL788157 | 0.84 | PFKFB3 (0.80) | PFKFB4PFKFB3CMA1NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113396145-A | PFKFB3 inhibitors and uses thereof | 盖罗发现有限责任公司 | 2021-09-14 | — | — | CN | disclosed |