SCHEMBL2864240

SCHEMBL2864240

CC(C)(c1ccc(O)cc1)c1ccc(OC(=O)C=CC(OCC2CO2)C2CO2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.46
TSHR P16473 3/20 0.46
MAPT P10636 3/20 0.46
TP53 P04637 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 1/20 0.46
PPARG P37231 1/20 0.46
HIF1A Q16665 1/20 0.46
MIF P14174 2/20 0.36
ESR1 P03372 2/20 0.33
CYP3A4 P08684 2/20 0.33
ESR2 Q92731 2/20 0.33
AR P10275 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
HTR6 P50406 1/20 0.33
ESRRG P62508 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633166 0.84 HPGD (0.45) HPGDTSHRMAPTTP53MEN1
SCHEMBL4021675 0.83 MAPT (0.44) HPGDTSHRMAPTTP53MEN1
SCHEMBL9011361 0.77 ALDH1A1 (0.51) HPGDTSHRMAPTTP53MEN1
SCHEMBL2701815 0.76 HPGD (0.43) HPGDTSHRMAPTTP53MEN1
Bicarbonate SCHEMBL10771552 0.74 TSHR (0.53) HPGDTSHRMAPTTP53MEN1
SCHEMBL21531599 0.74 ALDH1A1 (0.68) HPGDTSHRMAPTTP53MEN1
Fumaric Acid SCHEMBL11129348 0.74 ALDH1A1 (0.68) HPGDTSHRMAPTTP53MEN1
SCHEMBL12989580 0.73 ALDH1A1 (0.85) HPGDTSHRMAPTTP53MEN1
SCHEMBL156685 0.73 ALDH1A1 (0.85) HPGDTSHRMAPTTP53MEN1
SCHEMBL12990280 0.73 ALDH1A1 (0.85) HPGDTSHRMAPTTP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7709551-B2 Coating composition for film with low refractive index and film prepared therefrom LG CHEM, LTD. (KR) 2010-05-04 US claimed
EP-0394519-B1 Liquid crystal display panel incorporating an optical phase shifting substrate FUJIMORI KOGYO CO LTD (JP) 1994-02-02 EP disclosed
EP-0394519-A1 Liquid crystal display panel incorporating an optical phase shifting substrate FUJIMORI KOGYO CO., LTD. (JP) 1990-10-31 EP disclosed