SCHEMBL2864273

SCHEMBL2864273

Cc1cc(Cc2cc(C)cc(C(C)(C)C)c2[O])c([O])c(C(C)(C)C)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.62
SMN1; SMN2 Q16637 4/20 0.60
CYP2C9 P11712 3/20 0.60
CYP2C19 P33261 3/20 0.60
HIF1A Q16665 3/20 0.60
CYP2D6 P10635 2/20 0.53
HSD17B10 Q99714 1/20 0.53
ALDH1A1 P00352 2/20 0.46
CA2 P00918 1/20 0.46
POLB P06746 1/20 0.46
TYR P14679 1/20 0.46
AMY1A P0DUB6 1/20 0.34
KDM4E B2RXH2 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP1A2 P05177 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
ATP2A2 P16615 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL434782 0.81 ALDH1A1 (0.59) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL714574 0.78 CYP2C19 (0.38) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL29351672 0.77 HSPA5 (1.00) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL29415372 0.77 HSPA5 (1.00) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL34162 0.77 HSPA5 (1.00) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL4589719 0.76 HSPA5 (0.55) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL2253387 0.76 HSPA5 (0.53) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL11247674 0.75 CYP2C9 (1.00) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL29410654 0.75 HSPA5 (0.96) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL29357108 0.75 CYP2C9 (1.00) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10633497-B2 Methacrylic resin composition, molded article, film, and polarizing plate KURRAY CO., LTD. (JP) 2020-04-28 US disclosed
WO-2019188720-A1 NORBORNENE RING-OPENING POLYMER HYDRIDE AND METHOD FOR PRODUCING SAME 日本ゼオン株式会社 2019-10-03 WO disclosed
US-20190153135-A1 Activator Compositions, Their Preparation, And Their Use In Catalysts GRACE W R & CO (US) 2019-05-23 US disclosed
US-10221264-B2 Activator compositions, their preparation, and their use in catalysts W. R. GRACE & CO.-CONN. (US) 2019-03-05 US disclosed
EP-1795581-B1 LUBRICATING OIL COMPOSITION CONTAINING ACRYLIC POLYMER KURARAY CO (JP) 2018-09-19 EP disclosed
EP-3195846-A1 DENTAL POLYMERIZABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2017-07-26 EP disclosed
US-20170183463-A1 METHACRYLIC RESIN COMPOSITION, MOLDED ARTICLE, FILM, AND POLARIZING PLATE KURARAY CO., LTD. (JP) 2017-06-29 US disclosed
US-20150105238-A1 ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSTS W. R. GRACE & CO.-CONN. 2015-04-16 US disclosed
EP-2643366-B1 ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS ALBEMARLE CORP (US) 2015-03-25 EP disclosed
US-8895465-B2 Activator compositions, their preparation, and their use in catalysis ALBEMARLE CORPORATION (US) 2014-11-25 US disclosed
US-20130253155-A1 Activator Compositions, Their Preparation, and Their Use In Catalysis ALBEMARIE CORPORATION (US) 2013-09-26 US disclosed
WO-2012071205-A2 ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS ALBEMARLE CORPORATION (US) 2012-05-31 WO disclosed
US-7718588-B2 Lubricating oil additive containing acrylic polymer and lubricating oil compositions KURARAY CO., LTD. (JP) 2010-05-18 US disclosed
EP-1254922-B1 Polyalkoxyalkyl (meth)acrylates and preparation thereof TERUMO CORP (JP) 2008-12-17 EP disclosed
US-20080058234-A1 Lubricating Oil Additive Containing Acrylic Polymer and Lubricating Oil Compositions KURARAY CO., LTD. (JP) 2008-03-06 US disclosed
EP-1795581-A1 LUBRICATING OIL ADDITIVE CONTAINING ACRYLIC POLYMER AND LUBRICATING OIL COMPOSITIONS KURARAY CO., LTD. (JP) 2007-06-13 EP disclosed
US-6737493-B2 ANIONIC POLYMERIZED POLYALKOXYALKYL (METH)ACRYLATE, SUCH AS POLYMETHOXYETHYL ACRYLATE; MADE USING AN ARYLOXYALUMINUM COMPOUND AS CATALYST; USE SUCH AS ARTIFICIAL BODY PARTS, CATHETERS TERUMO KABUSHIKI KAISHA (JP) 2004-05-18 US disclosed
US-20020183472-A1 Biocompatible material TERUMO KABUSHIKI KAISHA (JP) 2002-12-05 US disclosed
EP-1254922-A2 Polyalkoxyalkyl (meth)acrylates and preparation thereof TERUMO KABUSHIKI KAISHA (JP) 2002-11-06 EP disclosed
EP-0557107-A2 Polyolefin resin and method for the preparation thereof IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1993-08-25 EP disclosed