SCHEMBL28643003

SCHEMBL28643003

NNC(=O)CNc1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.56
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
PKM P14618 1/20 0.50
CXCR4 P61073 1/20 0.49
ALDH1A1 P00352 3/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
FDPS P14324 1/20 0.47
FABP1 P07148 1/20 0.47
FABP6 P51161 1/20 0.47
HPGD P15428 1/20 0.46
CYP1A2 P05177 2/20 0.45
HDAC3 O15379 2/20 0.45
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC7 Q8WUI4 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC10 Q969S8 2/20 0.45
HDAC11 Q96DB2 2/20 0.45
HDAC8 Q9BY41 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22338218 0.83 GAA (0.56) GAANPC1RAB9APKMCXCR4
SCHEMBL2857962 0.82 GAA (0.55) GAANPC1RAB9APKMCXCR4
SCHEMBL9722609 0.82 GAA (0.58) GAANPC1RAB9APKMCXCR4
SCHEMBL28664986 0.81 GAA (0.53) GAANPC1RAB9APKMCXCR4
SCHEMBL534155 0.80 GAA (0.56) GAANPC1RAB9APKMCXCR4
Hydrochloric Acid SCHEMBL360682 0.80 GAA (0.56) GAANPC1RAB9APKMCXCR4
SCHEMBL25083223 0.80 GAA (0.53) GAANPC1RAB9APKMCXCR4
SCHEMBL22338149 0.79 GAA (0.51) GAANPC1RAB9APKMCXCR4
SCHEMBL13589538 0.79 GAA (0.55) GAANPC1RAB9APKMCXCR4
SCHEMBL7748124 0.78 GAA (0.50) GAANPC1RAB9APKMCXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113348017-A Hydrazide compound and kinase inhibitor 日产化学株式会社 2021-09-03 CN disclosed