Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.55 |
| ▸ | FABP1 | P07148 | 1/20 | 0.53 |
| ▸ | FABP6 | P51161 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534155 | 0.86 | GAA (0.56) | GAANPC1RAB9APKMCXCR4 | |
| Hydrochloric Acid SCHEMBL360682 | 0.86 | GAA (0.56) | GAANPC1RAB9APKMCXCR4 | |
| SCHEMBL13589538 | 0.85 | GAA (0.55) | GAANPC1RAB9APKMCXCR4 | |
| SCHEMBL2857962 | 0.85 | GAA (0.55) | GAANPC1RAB9APKMCXCR4 | |
| SCHEMBL28664986 | 0.83 | GAA (0.53) | GAANPC1RAB9APKMCXCR4 | |
| SCHEMBL28643003 | 0.82 | GAA (0.56) | GAANPC1RAB9APKMCXCR4 | |
| SCHEMBL22338218 | 0.82 | GAA (0.56) | GAANPC1RAB9APKMCXCR4 | |
| SCHEMBL7436411 | 0.82 | GAA (0.51) | GAANPC1RAB9APKMCXCR4 | |
| SCHEMBL15785585 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL7494264 | 0.80 | GAA (0.50) | GAANPC1RAB9APKMCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106986-A | PREPARATION OF AMINOETHANOL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-21 | — | — | US | claimed |
| EP-0450180-A2 | Process for the preparation of aminoethanol derivatives | BAYER AG (DE) | 1991-10-09 | — | — | EP | claimed |
| JP-4211658-A | — | — | None | — | — | JP | disclosed |
| JP-H04211658-A | PREPARATION OF AMINOETHANOL DERIVATIVE | BAYER AG | 1992-08-03 | — | — | JP | disclosed |
| US-5106986-A | PREPARATION OF AMINOETHANOL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-21 | — | — | US | disclosed |
| EP-0450180-A2 | Process for the preparation of aminoethanol derivatives | BAYER AG (DE) | 1991-10-09 | — | — | EP | disclosed |
| EP-0450180-A2 | Process for the preparation of aminoethanol derivatives | BAYER AG (DE) | 1991-10-09 | — | — | EP | disclosed |
| US-4895950-A | 5-halogeno-6-amino-nicotinic acid halides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-23 | — | — | US | disclosed |
| EP-0302227-A2 | 5-Halo-6-amino-nicotinic acid halides, their preparation and their use | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |