Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934754 | 1.00 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2PIK3R1PIK3CA | |
| SCHEMBL1260644 | 0.93 | PIK3R1 (0.49) | NPC1RAB9ASMN1; SMN2PIK3R1PIK3CA | |
| SCHEMBL30115073 | 0.93 | PIK3R1 (0.49) | NPC1RAB9ASMN1; SMN2PIK3R1PIK3CA | |
| SCHEMBL153714 | 0.92 | PIK3CD (0.54) | NPC1RAB9ASMN1; SMN2PIK3R1PIK3CA | |
| SCHEMBL31628325 | 0.92 | PIK3CD (0.54) | NPC1RAB9ASMN1; SMN2PIK3R1PIK3CA | |
| SCHEMBL19656225 | 0.92 | PIK3CD (0.54) | NPC1RAB9ASMN1; SMN2PIK3R1PIK3CA | |
| SCHEMBL153713 | 0.92 | PIK3CD (0.54) | NPC1RAB9ASMN1; SMN2PIK3R1PIK3CA | |
| SCHEMBL31594607 | 0.91 | PIK3R1 (0.42) | NPC1RAB9ASMN1; SMN2PIK3R1PIK3CA | |
| SCHEMBL9884066 | 0.91 | PIK3R1 (0.42) | NPC1RAB9ASMN1; SMN2PIK3R1PIK3CA | |
| SCHEMBL4412278 | 0.91 | PIK3R1 (0.42) | NPC1RAB9ASMN1; SMN2PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912599-B | Chemical entities, compositions, and methods | 英特利凯恩有限责任公司 | 2021-11-02 | — | — | CN | disclosed |