Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CPB1 | P15086 | 1/20 | 0.55 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.54 |
| ▸ | KLK7 | P49862 | 2/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16862463 | 1.00 | FOLH1 (0.56) | FOLH1MAPTCPB1CPB2SIRT2 | |
| SCHEMBL17039826 | 0.90 | FOLH1 (0.60) | FOLH1MAPTCPB1CPB2SIRT2 | |
| SCHEMBL2467817 | 0.90 | FOLH1 (0.65) | FOLH1MAPTCPB1CPB2SIRT2 | |
| SCHEMBL1491720 | 0.90 | FOLH1 (0.65) | FOLH1MAPTCPB1CPB2SIRT2 | |
| SCHEMBL699636 | 0.90 | FOLH1 (0.65) | FOLH1MAPTCPB1CPB2SIRT2 | |
| SCHEMBL31235777 | 0.90 | KLK7 (0.53) | MAPTCPB1CPB2SIRT2SIRT1 | |
| SCHEMBL7898675 | 0.90 | MMP1 (0.59) | MAPTSIRT2SIRT1KLK7KLK5 | |
| SCHEMBL5328146 | 0.89 | SIRT2 (0.66) | FOLH1MAPTCPB1CPB2SIRT2 | |
| SCHEMBL5328141 | 0.89 | SIRT2 (0.66) | FOLH1MAPTCPB1CPB2SIRT2 | |
| SCHEMBL31235764 | 0.89 | KLK7 (0.55) | MAPTCPB1CPB2SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114917361-A | Antibody Drug Conjugates (ADC) and antibody prodrug conjugates (APDC) with enzyme cleavable groups | 拜耳医药股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-107635586-B | Antibody-drug conjugates (ADC) of KSP inhibitors with aglycosylated anti-TWEAKR antibodies | 拜耳医药股份有限公司 | 2021-09-24 | — | — | CN | disclosed |