Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28921359 | 1.00 | KDM4E (0.33) | KDM4ECYP19A1CFTRGOPCSLC6A2 | |
| SCHEMBL28921258 | 1.00 | KDM4E (0.33) | KDM4ECYP19A1CFTRGOPCSLC6A2 | |
| SCHEMBL29571429 | 1.00 | KDM4E (0.33) | KDM4ECYP19A1CFTRGOPCSLC6A2 | |
| SCHEMBL29571827 | 1.00 | KDM4E (0.33) | KDM4ECYP19A1CFTRGOPCSLC6A2 | |
| SCHEMBL24931445 | 1.00 | KDM4E (0.33) | KDM4ECYP19A1CFTRGOPCSLC6A2 | |
| SCHEMBL24968597 | 1.00 | KDM4E (0.33) | KDM4ECYP19A1CFTRGOPCSLC6A2 | |
| SCHEMBL28643199 | 1.00 | KDM4E (0.33) | KDM4ECYP19A1CFTRGOPCSLC6A2 | |
| SCHEMBL25808302 | 0.85 | ALDH1A1 (0.36) | — | |
| SCHEMBL25808329 | 0.85 | ALDH1A1 (0.36) | — | |
| SCHEMBL14123444 | 0.84 | SMN1; SMN2 (0.33) | SLC6A3LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113475740-B | Preparation method of chiral synthetic nicotine | 深圳市真味生物科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114437029-A | Preparation method for asymmetric synthesis of chiral nicotine and chiral nicotine | 深圳市华加生物科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-113475740-A | Preparation method of chiral synthetic nicotine | 深圳市真味生物科技有限公司 | 2021-10-08 | — | — | CN | disclosed |