SCHEMBL28643207

SCHEMBL28643207

CO[C@H](C)C[C@@H](Br)C(=O)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
DGAT1 O75907 1/20 0.31
APP P05067 1/20 0.31
NOS1 P29475 2/20 0.31
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31
POLB P06746 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
ZDHHC7 Q9NXF8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22162338 1.00 CA12 (0.33) CA12CA14CA1CA2CA7
SCHEMBL28634515 1.00 CA12 (0.33) CA12CA14CA1CA2CA7
SCHEMBL28627760 1.00 CA12 (0.33) CA12CA14CA1CA2CA7
SCHEMBL22145578 1.00 CA12 (0.33) CA12CA14CA1CA2CA7
SCHEMBL9352351 0.84 KMT2A (0.33) CA12CA14CA1CA2CA7
SCHEMBL4634114 0.82 CA1 (0.38) CA1CA2CA7APPNOS1
SCHEMBL4634115 0.82 CA1 (0.38) CA1CA2CA7APPNOS1
SCHEMBL4385861 0.82 CA1 (0.38) CA1CA2CA7APPNOS1
SCHEMBL9352213 0.81 ZDHHC7 (0.43) CA12CA14CA1CA2CA7
SCHEMBL22162852 0.81 APLNR (0.34) APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113474348-A Substituted oxopyridine derivatives 拜耳公司 2021-10-01 CN disclosed