SCHEMBL28643270

SCHEMBL28643270

CC(O[SiH3])Oc1cccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 6/20 0.38
ADRA2B P18089 6/20 0.38
ADRA2C P18825 6/20 0.38
MAOB P27338 4/20 0.37
MAOA P21397 3/20 0.37
NISCH Q9Y2I1 1/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
ADRB2 P07550 2/20 0.35
HTR7 P34969 1/20 0.34
MAPK1 P28482 2/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28729614 0.86 ADRA2A (0.48) ADRA2AADRA2BADRA2CMAOBMAOA
SCHEMBL18784858 0.77 MAPK1 (0.39) ADRB2HTR7MAPK1LMNAMAPT
SCHEMBL28395476 0.75 HTT (0.36) CA1CA2CA7CA9MAPK1
SCHEMBL895721 0.73 FGFR1 (0.49) CA1CA2CA7CA9HTR7
SCHEMBL8602820 0.73 NCOA1 (0.46) ADRB2HTR7MAPK1LMNAMAPT
SCHEMBL30673426 0.73 NCOA1 (0.46) ADRB2HTR7MAPK1LMNAMAPT
Hydrochloric Acid SCHEMBL27439165 0.72 MAPK1 (0.42) ADRB2HTR7MAPK1LMNAMAPT
SCHEMBL17874338 0.71 CA1 (0.46) ADRA2AADRA2BADRA2CNISCHCA1
SCHEMBL1839351 0.70 CD274 (0.38) ADRA2AADRA2BADRA2CMAOBMAOA
SCHEMBL28728785 0.70 NISCH (0.42) ADRA2BNISCHADRB2MAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715680-B Process for preparing high cis-1, 4-polydienes with lanthanide-based catalyst compositions 株式会社普利司通 2021-10-19 CN disclosed