Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.73 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.73 |
| ▸ | DRD3 | P35462 | 8/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD5 | P21918 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354894 | 0.96 | DRD2 (0.75) | DRD2SIGMAR1DRD3HTR6SLC6A4 | |
| SCHEMBL17364137 | 0.96 | DRD2 (0.75) | DRD2SIGMAR1DRD3HTR6SLC6A4 | |
| SCHEMBL17368147 | 0.91 | DRD2 (0.67) | DRD2SIGMAR1DRD3HTR6SLC6A4 | |
| SCHEMBL17366554 | 0.89 | DRD2 (0.65) | DRD2SIGMAR1DRD3HTR6SLC6A4 | |
| SCHEMBL25690904 | 0.87 | DRD2 (0.62) | DRD2SIGMAR1DRD3HTR6SLC6A4 | |
| SCHEMBL17366553 | 0.86 | DRD2 (0.61) | DRD2SIGMAR1DRD3HTR6SLC6A4 | |
| Pridopidine SCHEMBL166748 | 0.85 | DRD2 (1.00) | DRD2SIGMAR1DRD3HTR6SLC6A4 | |
| Pridopidine SCHEMBL29664816 | 0.85 | DRD2 (1.00) | DRD2SIGMAR1DRD3HTR6SLC6A4 | |
| Pridopidine SCHEMBL15007479 | 0.84 | DRD2 (0.97) | DRD2SIGMAR1DRD3HTR6SLC6A4 | |
| Pridopidine SCHEMBL2370301 | 0.84 | DRD2 (0.97) | DRD2SIGMAR1DRD3HTR6SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113511997-A | Pridopidine analogues, their preparation and use | 普丽莱尼亚神经治疗有限公司 | 2021-10-19 | — | — | CN | disclosed |
| CN-113511997-A | Pridopidine analogues, their preparation and use | 普丽莱尼亚神经治疗有限公司 | 2021-10-19 | — | — | CN | disclosed |