Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28644209 | 1.00 | MEN1 (0.38) | MEN1KMT2ACARM1PRMT6PPARD | |
| SCHEMBL28644766 | 0.83 | CARM1 (0.36) | MEN1KMT2ACARM1PRMT6PPARD | |
| SCHEMBL28857928 | 0.83 | CYP1A2 (0.41) | MEN1KMT2ACARM1PRMT6LMNA | |
| SCHEMBL21494355 | 0.80 | L3MBTL1 (0.38) | MEN1KMT2ACARM1PRMT6KDM4E | |
| SCHEMBL21494351 | 0.80 | L3MBTL1 (0.38) | MEN1KMT2ACARM1PRMT6KDM4E | |
| SCHEMBL21494319 | 0.80 | KDM4E (0.41) | MEN1KMT2ACARM1PRMT6LMNA | |
| SCHEMBL21494320 | 0.80 | KDM4E (0.41) | MEN1KMT2ACARM1PRMT6LMNA | |
| SCHEMBL23070818 | 0.79 | SMN1; SMN2 (0.37) | MEN1KMT2ACARM1PRMT6LMNA | |
| SCHEMBL23070821 | 0.79 | SMN1; SMN2 (0.37) | MEN1KMT2ACARM1PRMT6LMNA | |
| SCHEMBL23070820 | 0.79 | SMN1; SMN2 (0.37) | MEN1KMT2ACARM1PRMT6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110386945-B | Macrocyclic kinase inhibitor | 广州白云山医药集团股份有限公司白云山制药总厂 | 2021-09-28 | — | — | CN | disclosed |