Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 8/20 | 0.65 |
| ▸ | MAOA | P21397 | 4/20 | 0.65 |
| ▸ | LOXL2 | Q9Y4K0 | 15/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28657417 | 0.89 | LOXL2 (0.65) | LOXMAOALOXL2KCNH2AOC3 | |
| SCHEMBL28657105 | 0.87 | LOXL2 (0.64) | LOXMAOALOXL2KCNH2AOC3 | |
| SCHEMBL28927270 | 0.81 | LOXL2 (0.49) | LOXMAOALOXL2KCNH2AOC3 | |
| SCHEMBL28927224 | 0.81 | LOX (0.66) | LOXMAOALOXL2KCNH2AOC3 | |
| SCHEMBL19259962 | 0.79 | LOX (1.00) | LOXMAOALOXL2KCNH2AOC3 | |
| Hydrochloric Acid SCHEMBL28638853 | 0.79 | LOXL2 (0.68) | LOXMAOALOXL2KCNH2 | |
| SCHEMBL28644288 | 0.78 | LOX (0.63) | LOXMAOALOXL2KCNH2AOC3 | |
| SCHEMBL28638918 | 0.78 | LOX (0.69) | LOXMAOALOXL2KCNH2AOC3 | |
| SCHEMBL28927255 | 0.77 | LOX (0.53) | LOXMAOALOXL2KCNH2AOC3 | |
| SCHEMBL28643887 | 0.77 | LOX (0.59) | LOXLOXL2KCNH2AOC3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |