SCHEMBL28644256

SCHEMBL28644256

C=CC(=O)OCC(=O)Oc1ccccc1.C=Cc1ccccc1C=C

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.51
CYP19A1 P11511 1/20 0.38
MAOB P27338 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
ALDH1A1 P00352 2/20 0.36
GAA P10253 2/20 0.36
HPGD P15428 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.36
ALOX15 P16050 1/20 0.35
ELANE P08246 1/20 0.35
PDE6D O43924 1/20 0.34
TGM2 P21980 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12376682 0.80 THRB (0.46) THRBCYP19A1MEN1KMT2AALDH1A1
SCHEMBL18258053 0.78 THRB (0.49) THRBKMT2AALDH1A1GAAHPGD
SCHEMBL12038758 0.78 THRB (0.45) THRBKMT2AALDH1A1GAAHPGD
SCHEMBL18027478 0.77 THRB (0.64) THRBCYP19A1KMT2APRSS1PRSS2
SCHEMBL20496776 0.77 KMT2A (0.46) THRBMEN1KMT2AALDH1A1HPGD
SCHEMBL28105352 0.75 HCAR2 (0.56) THRBMAOBKMT2AALDH1A1TGM2
Hydrogen Peroxide SCHEMBL28479331 0.75 THRB (0.58) THRBMAOBMEN1KMT2AALDH1A1
SCHEMBL28916 0.75 THRB (0.58) THRBMAOBMEN1KMT2AALDH1A1
Acrylic Acid Ethyl Ester SCHEMBL10887714 0.74 THRB (0.47) THRBMEN1KMT2AALDH1A1HPGD
SCHEMBL3680375 0.74 CYP3A4 (0.53) THRBMEN1KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113544219-A Black aluminum pigment and method for producing same 东洋铝株式会社 2021-10-22 CN disclosed