SCHEMBL28644458

SCHEMBL28644458

Oc1ccc(OC2CCCOC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACACB O00763 3/20 0.46
PARP10 Q53GL7 1/20 0.40
GRM5 P41594 3/20 0.39
FURIN P09958 2/20 0.38
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
HRH3 Q9Y5N1 2/20 0.35
CHEK1 O14757 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL337476 0.89 ACACB (0.42) ACACBHRH3CHEK1
SCHEMBL21051305 0.89 ACACB (0.42) ACACBHRH3CHEK1
SCHEMBL21051334 0.89 ACACB (0.42) ACACBHRH3CHEK1
SCHEMBL19166246 0.85 CHEK1 (0.43) ACACBHRH3CHEK1ESR1ESR2
SCHEMBL9939064 0.83 ACACB (0.44) ACACBPARP10GRM5FURINALDH1A1
SCHEMBL12362151 0.82 ACACB (0.44) ACACBPARP10GRM5FURINALDH1A1
SCHEMBL21051593 0.81 ESR2 (0.42) ACACBPARP10ALDH1A1MEN1KMT2A
SCHEMBL22657500 0.80 ACACB (0.50) ACACBALDH1A1TSHRHRH3
SCHEMBL20506959 0.79 ACACB (0.41) ACACBPARP10GRM5FURINHRH3
SCHEMBL1837838 0.79 PARP10 (0.53) PARP10FURINALDH1A1TSHRHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108289819-B Anhydrous spot-removing composition containing phenolic compounds 杭州鼎智生物医药有限公司 2021-09-10 CN disclosed