SCHEMBL19166246

SCHEMBL19166246

Oc1ccc(-c2ccc(OC3CCOC3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.43
ESR2 Q92731 2/20 0.40
ACACB O00763 3/20 0.40
APP P05067 1/20 0.38
SLC5A2 P31639 4/20 0.37
SLC5A1 P13866 3/20 0.37
HRH3 Q9Y5N1 2/20 0.37
BTK Q06187 1/20 0.37
ESR1 P03372 1/20 0.37
IRAK4 Q9NWZ3 1/20 0.36
GPR119 Q8TDV5 1/20 0.36
LIPG Q9Y5X9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21051305 0.95 ACACB (0.42) CHEK1ACACBSLC5A2SLC5A1HRH3
SCHEMBL337476 0.95 ACACB (0.42) CHEK1ACACBSLC5A2SLC5A1HRH3
SCHEMBL21051334 0.95 ACACB (0.42) CHEK1ACACBSLC5A2SLC5A1HRH3
SCHEMBL28644458 0.85 ACACB (0.46) CHEK1ESR2ACACBHRH3ESR1
SCHEMBL14603517 0.84 LIPG (0.45) ESR2ACACBAPPHRH3ESR1
SCHEMBL23980995 0.83 NPC1 (0.42) GPR119
SCHEMBL15717432 0.81 ALDH1A1 (0.53) ACACBAPP
SCHEMBL15717433 0.81 ALDH1A1 (0.53) ACACBAPP
SCHEMBL15717703 0.81 ALDH1A1 (0.53) ACACBAPP
SCHEMBL31593209 0.81 SLC5A2 (0.58) CHEK1SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10190050-B2 Liquid crystal composition, liquid crystal display device including the same, and method of manufacturing liquid crystal display device SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-29 US disclosed
US-20170210994-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME, AND METHOD OF MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2017-07-27 US disclosed
US-20170210994-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME, AND METHOD OF MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2017-07-27 US disclosed