SCHEMBL2864488

SCHEMBL2864488

CCCC[C]1C(CCCC)=C(CCCC)c2c(CCCC)cccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.38
CTSG P08311 4/20 0.38
BID P55957 3/20 0.36
MCL1 Q07820 3/20 0.36
BCL2L1 Q07817 2/20 0.36
BAK1 Q16611 2/20 0.36
KAT8 Q9H7Z6 2/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
EP300 Q09472 1/20 0.36
KAT2A Q92830 1/20 0.36
KAT2B Q92831 1/20 0.36
KAT5 Q92993 1/20 0.36
SAE1 Q9UBE0 1/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
LIPG Q9Y5X9 1/20 0.35
ALOX5 P09917 1/20 0.35
PTGS2 P35354 1/20 0.35
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2863962 0.82 ELANE (0.36) ELANECTSG
SCHEMBL2860991 0.78 TYR (0.35) ELANECTSGALOX5CYP3A4TYR
SCHEMBL2867248 0.76 TDP1 (0.35) NR1H2NR1H3LIPG
SCHEMBL2862472 0.71 NPC1 (0.33) TYR
SCHEMBL2701240 0.71 LIPG (0.50) ELANECTSGPPARANR1H2NR1H3
SCHEMBL2963335 0.71 PTPN1 (0.41) KAT2BNR1H2NR1H3LIPGALOX5
SCHEMBL7707048 0.70 PDCD1 (0.44) ELANECTSGBIDMCL1BCL2L1
SCHEMBL27836089 0.70 PDCD1 (0.44) ELANECTSGBIDMCL1BCL2L1
SCHEMBL1516923 0.70 ELANE (0.49) ELANECTSGBIDMCL1BCL2L1
SCHEMBL8674733 0.70 LIPG (0.41) ELANECTSGBIDMCL1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
EP-1473323-B1 Polyethylene composition and process for producing same TOSOH CORP (JP) 2016-04-27 EP disclosed
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
EP-1964860-A1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER Tosoh Corporation (JP) 2008-09-03 EP disclosed
US-7166684-B2 Transition metal compound, catalyst for olefin polymerization and method for producing polyolefin JAPAN POLYETHYLENE CORPORATION (JP) 2007-01-23 US disclosed
US-20060167196-A1 Novel transition metal compound, catalyst for olefin polymerization and method for producing polyolefin JAPAN POLYETHYLENE CORPORATION (JP) 2006-07-27 US disclosed
EP-1473323-A1 Polyethylene composition and process for producing same Tosoh Corporation (JP) 2004-11-03 EP disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167196-A1 Novel transition metal compound, catalyst for olefin polymerization and method for producing polyolefin PCLAF, ZKSCAN2, POF1B ELANE 3898/4885CTSG 3414/4885BID 2274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.