Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28653173 | 0.78 | SMN1; SMN2 (0.51) | MAPTALDH1A1KDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL6844201 | 0.77 | KDM4E (0.48) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL28647431 | 0.77 | CYP1A2 (0.51) | MEN1KMT2AGAAMAPTALDH1A1 | |
| Bromide SCHEMBL28658159 | 0.77 | SMN1; SMN2 (0.50) | MAPTALDH1A1KDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL15505756 | 0.75 | PLK1 (0.64) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL21652210 | 0.73 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4ERXFP1SMN1; SMN2 | |
| SCHEMBL21652212 | 0.73 | MEN1 (0.56) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL485110 | 0.72 | CNR2 (0.44) | MAPTKDM4ERXFP1SMN1; SMN2NPC1 | |
| SCHEMBL6592127 | 0.72 | F10 (0.56) | MEN1KMT2AGAANPC1RAB9A | |
| SCHEMBL12918684 | 0.72 | SMN1; SMN2 (0.64) | MEN1KMT2AGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372184-B | Method for synthesizing C-N axis chiral phenanthridinone compound based on chiral transfer strategy | 武汉大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-113372184-A | Method for synthesizing C-N axis chiral phenanthridinone compound based on chiral transfer strategy | 武汉大学 | 2021-09-10 | — | — | CN | disclosed |