Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL29051861 | 1.00 | FOLH1 (0.47) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL20492167 | 0.89 | GSR (0.51) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL18441019 | 0.89 | GSR (0.51) | FOLH1GSRDPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL10879089 | 0.87 | GSR (0.50) | FOLH1GSRDPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL10879193 | 0.87 | GSR (0.50) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL1070057 | 0.87 | GSR (0.60) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL20723487 | 0.87 | GSR (0.60) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL17696519 | 0.87 | GSR (0.60) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL20723484 | 0.87 | GSR (0.60) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL8616589 | 0.87 | GSR (0.60) | FOLH1GSRDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621700-B | Method for GalNAc oligonucleotide conjugates | 豪夫迈·罗氏有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-107709342-B | Process for preparing acetylgalactosamine acid derivatives | 豪夫迈·罗氏有限公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-110621700-A | Methods for GalNAc oligonucleotide conjugates | 豪夫迈·罗氏有限公司 | 2019-12-27 | — | — | CN | disclosed |