Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 9/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18084492 | 1.00 | FKBP1A (0.50) | FKBP1AKLK7PARP1CTSLMEN1 | |
| SCHEMBL933969 | 1.00 | FKBP1A (0.50) | FKBP1AKLK7PARP1CTSLMEN1 | |
| SCHEMBL18084467 | 0.89 | KLK7 (0.48) | FKBP1AKLK7PARP1CTSLMEN1 | |
| SCHEMBL935047 | 0.89 | KLK7 (0.48) | FKBP1AKLK7PARP1CTSLMEN1 | |
| SCHEMBL6787776 | 0.88 | FKBP1A (0.49) | FKBP1AKLK7PARP1CTSLPDK1 | |
| SCHEMBL204505 | 0.88 | FKBP1A (0.49) | FKBP1AKLK7PARP1CTSLPDK1 | |
| SCHEMBL204506 | 0.88 | FKBP1A (0.49) | FKBP1AKLK7PARP1CTSLPDK1 | |
| SCHEMBL29447560 | 0.86 | FKBP1A (0.58) | FKBP1AKLK7CTSLMEN1KMT2A | |
| SCHEMBL7404715 | 0.86 | FKBP1A (0.58) | FKBP1AKLK7CTSLMEN1KMT2A | |
| SCHEMBL5970730 | 0.84 | KLK7 (0.66) | FKBP1AKLK7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114599372-A | Combination therapy for the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-113395996-A | Arginase inhibitors and methods of use thereof | 阿斯利康(瑞典)有限公司 | 2021-09-14 | — | — | CN | disclosed |