Coumarin-3-Carboxylic Acid

Coumarin-3-Carboxylic Acid

SCHEMBL28645274

O=C(O)c1cc2ccccc2oc1=O.[NaH]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.96
CA12 O43570 3/20 0.96
CA9 Q16790 3/20 0.96
GPR35 Q9HC97 3/20 0.96
CA1 P00915 2/20 0.96
CA4 P22748 2/20 0.96
CA6 P23280 2/20 0.96
CA5A P35218 2/20 0.96
CA7 P43166 2/20 0.96
CA14 Q9ULX7 2/20 0.96
CA5B Q9Y2D0 2/20 0.96
CA3 P07451 1/20 0.96
TSHR P16473 1/20 0.96
KDM4E B2RXH2 5/20 0.70
CYP1A2 P05177 2/20 0.70
NT5E P21589 1/20 0.70
NPC1 O15118 2/20 0.67
RAB9A P51151 2/20 0.67
MEN1 O00255 1/20 0.67
KMT2A Q03164 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumarin-3-Carboxylic Acid SCHEMBL29414591 0.98 MAOB (1.00) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL93571 0.98 MAOB (1.00) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL28133841 0.96 MAOB (0.96) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL31756871 0.96 MAOB (0.96) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL31756872 0.96 MAOB (0.96) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL7862224 0.96 MAOB (0.96) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL9551102 0.95 MAOB (0.93) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL27939837 0.89 MAOB (0.82) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL28874726 0.86 MAOB (0.77) MAOBCA12CA9GPR35CA1
SCHEMBL34468463 0.85 MAOB (0.77) MAOBCA12CA9GPR35CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113355093-B Fluorescent sensing material based on rare earth hybrid layered material and preparation method and application thereof 河北师范大学 2022-08-02 CN claimed
CN-113355093-A Fluorescent sensing material based on rare earth hybrid layered material and preparation method and application thereof 河北师范大学 2021-09-07 CN claimed
CN-113355093-B Fluorescent sensing material based on rare earth hybrid layered material and preparation method and application thereof 河北师范大学 2022-08-02 CN disclosed
CN-113355093-A Fluorescent sensing material based on rare earth hybrid layered material and preparation method and application thereof 河北师范大学 2021-09-07 CN disclosed