Coumarin-3-Carboxylic Acid

Coumarin-3-Carboxylic Acid

SCHEMBL29414591

O=C(O)c1cc2ccccc2oc1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 1.00
CA12 O43570 3/20 1.00
CA9 Q16790 3/20 1.00
GPR35 Q9HC97 3/20 1.00
CA1 P00915 2/20 1.00
CA4 P22748 2/20 1.00
CA6 P23280 2/20 1.00
CA5A P35218 2/20 1.00
CA7 P43166 2/20 1.00
CA14 Q9ULX7 2/20 1.00
CA5B Q9Y2D0 2/20 1.00
CA3 P07451 1/20 1.00
TSHR P16473 1/20 1.00
KDM4E B2RXH2 5/20 0.72
CYP1A2 P05177 2/20 0.72
NT5E P21589 1/20 0.72
NPC1 O15118 2/20 0.68
RAB9A P51151 2/20 0.68
MEN1 O00255 1/20 0.68
KMT2A Q03164 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumarin-3-Carboxylic Acid SCHEMBL93571 1.00 MAOB (1.00) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL28133841 0.98 MAOB (0.96) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL28645274 0.98 MAOB (0.96) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL31756872 0.98 MAOB (0.96) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL31756871 0.98 MAOB (0.96) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL7862224 0.98 MAOB (0.96) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL9551102 0.96 MAOB (0.93) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL27939837 0.91 MAOB (0.82) MAOBCA12CA9GPR35CA1
Coumarin-3-Carboxylic Acid SCHEMBL28874726 0.88 MAOB (0.77) MAOBCA12CA9GPR35CA1
SCHEMBL34468463 0.87 MAOB (0.77) MAOBCA12CA9GPR35CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037242-A Ultraviolet light controlled light reversible dynamic cross-linked polymer material with reversible antibacterial, shape deformation and toughening functions, preparation method and application thereof 扬州大学 2026-05-15 CN claimed
EP-4683951-A2 METHOD OF FUNCTIONALIZATION OF A BIOPOLYMER AND METHOD OF CROSS-LINKING THEREOF Polbionica Spolka Akcyjna (PL) 2026-01-28 EP claimed
CN-118560124-B Antibacterial breathable knitted fabric and preparation method thereof 如东鑫利纺织有限公司 2024-11-19 CN claimed
WO-2024196271-A2 METHOD OF FUNCTIONALIZATION OF A BIOPOLYMER AND METHOD OF CROSS-LINKING THEREOF POLBIONICA SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) 2024-09-26 WO claimed
CN-118639461-A Preparation method and application of multi-stimulus response anti-counterfeiting paper based on chestnut shells and coumarin 浙江科技大学 2024-09-13 CN claimed
CN-118271608-A Water-soluble polyamide resin, high-temperature-resistant chip plasma cutting protection liquid, and preparation method and application thereof 浙江奥首材料科技有限公司 2024-07-02 CN claimed
WO-2022199685-A1 NUCLEIC ACID MOLECULE CONJUGATE HAVING PROLONGED IN VIVO HALF-LIFE 安沛治疗有限公司 2022-09-29 WO claimed
CN-122037242-A Ultraviolet light controlled light reversible dynamic cross-linked polymer material with reversible antibacterial, shape deformation and toughening functions, preparation method and application thereof 扬州大学 2026-05-15 CN disclosed
CN-122037242-A Ultraviolet light controlled light reversible dynamic cross-linked polymer material with reversible antibacterial, shape deformation and toughening functions, preparation method and application thereof 扬州大学 2026-05-15 CN disclosed
EP-4683951-A2 METHOD OF FUNCTIONALIZATION OF A BIOPOLYMER AND METHOD OF CROSS-LINKING THEREOF Polbionica Spolka Akcyjna (PL) 2026-01-28 EP disclosed
US-20250376393-A1 SELF-REGENERATING GRAPHENE OXIDE-BASED ADSORBENTS FOR CONTAMINANT REMOVAL FROM AQUEOUS SYSTEMS UNIV NORTHWESTERN (US) 2025-12-11 US disclosed
US-20250346575-A1 ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2025-11-13 US disclosed
CN-120081905-A Mussel poda-based antioxidant peptide, preparation method, preparation and application thereof 成都大学 2025-06-03 CN disclosed
WO-2022238741-A1 COUMARIN COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF MAJUMDER SUMAN (IN) 2022-11-17 WO disclosed
WO-2022199685-A1 NUCLEIC ACID MOLECULE CONJUGATE HAVING PROLONGED IN VIVO HALF-LIFE 安沛治疗有限公司 2022-09-29 WO disclosed
US-11452983-B2 Combination of isolated individual enhancements of X-ray radiation effect by nanomaterials THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-09-27 US disclosed
CN-107382932-B Coumarin carboxylic acid shikonin ester derivative and synthesis method and application thereof 南京大学 2022-07-29 CN disclosed
CN-107382932-B Coumarin carboxylic acid shikonin ester derivative and synthesis method and application thereof 南京大学 2022-07-29 CN disclosed
WO-2022090819-A1 NON-TOXIC FUROCOUMARIN-RICH PLANT EXTRACTS AND RELATED COMPOSITIONS FOR USE AS ANTIMICROBIAL SUBSTANCE OR MEDICAMENT AND OTHER THERAPEUTIC USES ICE-P LIFE, S.L. (ES) 2022-05-05 WO disclosed
CN-112175195-B Supramolecular polymer gel, preparation thereof and application of supramolecular polymer gel in fluorescent recognition of iron ions and fluorine ions 陇东学院 2022-02-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346575-A1 ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF CRBN, IDH1, IDH2 MAOB 3482/4885CA12 3334/4885CA9 4036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.