Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.46 |
| ▸ | GRM5 | P41594 | 11/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21245894 | 0.79 | CYP11B2 (0.56) | GRM1GRM5PDK4BTKTNK2 | |
| SCHEMBL31479190 | 0.78 | GRM1 (0.48) | GRM1GRM5PDK4TNK2NAMPT | |
| SCHEMBL60338 | 0.78 | GRM1 (0.46) | GRM1GRM5PDK4BTKTNK2 | |
| SCHEMBL522295 | 0.77 | ALK (0.56) | — | |
| SCHEMBL5081066 | 0.77 | TNK2 (0.46) | GRM1GRM5PDK4BTKTNK2 | |
| SCHEMBL31479575 | 0.75 | GRM1 (0.52) | GRM1GRM5PDK4TNK2CYP11B2 | |
| SCHEMBL27167704 | 0.74 | GRM1 (0.53) | GRM1GRM5PDK4BTKTNK2 | |
| SCHEMBL29803742 | 0.74 | NAMPT (0.54) | GRM1GRM5PDK4BTKTNK2 | |
| SCHEMBL30198712 | 0.74 | GRM1 (0.55) | GRM1GRM5PDK4BTKTNK2 | |
| SCHEMBL13096687 | 0.74 | GRM1 (0.55) | GRM1GRM5PDK4BTKTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493439-A | Substituted acrylamide derivative, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-113336760-A | Substituted amide derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-09-03 | — | — | CN | disclosed |