Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499237 | 0.91 | ADORA2A (0.64) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL3499233 | 0.91 | ADORA2A (0.64) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL2761074 | 0.85 | MEN1 (0.66) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL3500482 | 0.85 | MEN1 (0.66) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL2480941 | 0.83 | ADORA2A (0.62) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL23895160 | 0.83 | TSHR (0.60) | ADORA2AADORA3ADORA2BTP53CYP3A4 | |
| SCHEMBL31160207 | 0.83 | TSHR (0.60) | ADORA2AADORA3ADORA2BTP53CYP3A4 | |
| SCHEMBL21063153 | 0.83 | TSHR (0.60) | ADORA2AADORA3ADORA2BTP53CYP3A4 | |
| SCHEMBL21877981 | 0.83 | TSHR (0.60) | ADORA2AADORA3ADORA2BTP53CYP3A4 | |
| SCHEMBL31160202 | 0.83 | TSHR (0.60) | ADORA2AADORA3ADORA2BTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109694397-B | Cyclic dinucleotide compounds, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2021-08-31 | — | — | CN | disclosed |