Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29047905 | 0.92 | ADORA2A (0.60) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL29047902 | 0.92 | ADORA2A (0.60) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL3499237 | 0.92 | ADORA2A (0.64) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL3499233 | 0.92 | ADORA2A (0.64) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL31439427 | 0.89 | ADORA2A (0.61) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL3692894 | 0.88 | PRMT5 (0.60) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL30208574 | 0.88 | LMNA (0.60) | ADORA2AADORA2BTSHRNFKB1ALDH1A1 | |
| SCHEMBL30208584 | 0.88 | ADORA2A (0.59) | ADORA2AADORA2BALDH1A1PMP22 | |
| SCHEMBL453953 | 0.87 | ADORA2A (0.57) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL453954 | 0.87 | ADORA2A (0.57) | ADORA2AADORA2BTP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316030-B1 | PROTEIN SCREEING METHODS | WAGNER RICHARD W (US) | 2019-08-21 | — | — | EP | claimed |
| EP-1712623-B1 | Selection of proteins using RNA-protein fusions | GEN HOSPITAL CORP (US) | 2011-10-19 | — | — | EP | claimed |
| CN-1238366-C | Selection of proteins using RNA-protein fusions | GEN HOSPITAL CORP (US) | 2006-01-25 | — | — | CN | disclosed |
| CN-1251593-A | Selection of proteins using RNA-protein fusions | GEN HOSPITAL CORP (US) | 2000-04-26 | — | — | CN | disclosed |