SCHEMBL28645568

SCHEMBL28645568

CC(C)CC(F)=Cc1ccc2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
GAA P10253 1/20 0.44
RAB9A P51151 1/20 0.44
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
RELA Q04206 1/20 0.41
PTGS1 P23219 1/20 0.40
UGT2B7 P16662 1/20 0.40
NQO2 P16083 2/20 0.38
GLA P06280 1/20 0.38
MAPT P10636 1/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28646816 1.00 SMN1; SMN2 (0.44) SMN1; SMN2GAARAB9AALDH1A1KDM4E
SCHEMBL28645567 1.00 SMN1; SMN2 (0.44) SMN1; SMN2GAARAB9AALDH1A1KDM4E
SCHEMBL6960044 0.80 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1KDM4EL3MBTL1RELA
SCHEMBL6960053 0.80 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1KDM4EL3MBTL1RELA
SCHEMBL6960049 0.80 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1KDM4EL3MBTL1RELA
SCHEMBL28636663 0.78 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1KDM4EL3MBTL1RELA
SCHEMBL28638864 0.78 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1KDM4EL3MBTL1RELA
SCHEMBL31172199 0.75 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1KDM4EL3MBTL1RELA
SCHEMBL29639038 0.75 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1KDM4EL3MBTL1RELA
SCHEMBL10049312 0.75 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1KDM4EL3MBTL1RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447521-B Reagent for preparing high-selectivity monofluoroolefin 中国科学院上海有机化学研究所 2021-09-03 CN disclosed